I will not be buying anything with always-on DRM. I've echoed this a million times, but it needs to be seen by any of these bastards where it might count. I've have even sent emails to Ubisoft and EA. Really want to play ME3 and BF3, but if this really is the road they take, no thanks. That's all I have to say about it, until the games are actually released.
However, game companies that support opening a new game and playing straight away without connecting first, updating, or installing 3rd party crap, I will support whole-heartedly.