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Phoenixmgs

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Based on you reckoning so?



More irrelevant anecdote.

You have an immune system, buddy. Everyone does. Sometimes it wins out; sometimes it doesn't.

Only you would interpret the fact you didn't get sick from something as proof that nobody gets sick from that thing.
You've provided no actual data that anything you said is true. Then you get mad when basic observation of the world around me disproves that. You do not realize how the world would be if what you said is true (a normal infectious dose was only a tiny fraction of a sneeze/cough). How would anyone (not just super lucky me) be able to go to a packed theater/bar/convention/cruise ship/New Year's party/etc and not get sick? Also, an infectious dose needs to get past your immune system to be an infectious dose, it's like part of the definition...

You're like the football analytics people that kept saying Geno Smith is a top 5 quarterback based on advanced metrics when I observed him play and know he's not an elite quarterback.
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Funny how you ignore science saying that there is low evidence the common cold transfers via surfaces in a significant manner.
 
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Satinavian

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I do enjoy when democraps pretend to relevance.
Honestly it is time the democrats tried a left leaning candidate. Centrists don't work. Sure, they might not spook some voters in the middle, but they also fail to get grassroot movements mobilized.
 

Schadrach

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Interesting. I eagerly await the many benefits this new vibes-based approach to science will no doubt have.
Ivermectin is also a powerful antiviral, just only in doses much higher than you give someone, or are safe to give someone. I imagine it's at least as effective for cancer. It can definitely kill a tumor with a high enough dose, just whether that dose is above or below LD-50 remains to be seen.
 

Phoenixmgs

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Data on how much is shed in a single sneeze. Data on what the infectious dose is.



Not "mad" exactly; I disregard your meaningless anecdotes.
Data on infectious dose has basically no validity, which is why your claim makes no sense based on simple observation of the real world.

How would one ever go to a crowed indoor gathering for hours and not get sick? What you're trying to claim would make that literally impossible, yet we all know that happens all the time.

You retracting your claim about clusters of people getting sick from touching surfaces at the store yet?
 

dreng3

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Ivermectin is also a powerful antiviral, just only in doses much higher than you give someone, or are safe to give someone. I imagine it's at least as effective for cancer. It can definitely kill a tumor with a high enough dose, just whether that dose is above or below LD-50 remains to be seen.
One must remember that there is always a relevant XKCD and that it should always be posted. I appreciate that we're doing research, but not everything should be hailed as a miracle or a grand discovery.

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Silvanus

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Data on infectious dose has basically no validity, which is why your claim makes no sense based on simple observation of the real world.
You are the one who brought up infectious dose.

You retracting your claim about clusters of people getting sick from touching surfaces at the store yet?
...why would I? You haven't provided anything aside from your meaningless anecdotes. I'll stick with the well-established fact that fomite transmission is a common vector for various common viruses.
 
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The Rogue Wolf

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Hades

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A Texas jury decided that it's perfectly okay to shoot your own daughter dead in a drunken rage if she said bad things about Trump.


Note to self: Stay the fuck away from Texas; they're insane there.

And that’s the problem with jury duty. If you leave law in the hands of complete rando’s they might decide killing people shouldn’t be punished if the rando’s turn out to be inbred hicks.
 

Agema

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Agema

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Interesting. I eagerly await the many benefits this new vibes-based approach to science will no doubt have.
Ivermectin is indeed under examination for cancer, and it's a perfectly reasonable thing to fund.

However, a persistent issue with the current leaders of US healthcare is that they still want to fight Covid-19: you can barely get through a few minutes of podcast without them explaining their hurt feelings that they were very publicly shown to be wrong 5 years ago. Of course they're obsessed with refighting that war, and ivermectin is one of these. So a load of ivermectin cranks, having had the drug demonstrated useless against covid, are now obsessed with the idea it can treat anything else. Because if it does, it can feel like some sort of vindication that they were guzzling it by the truckload in 2020.
 
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Chimpzy

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Ivermectin is indeed under examination for cancer, and it's a perfectly reasonable thing to fund.

However, a persistent issue with the current leaders of US healthcare is that they still want to fight Covid-19: you can barely get through a few minutes of podcast without them explaining their hurt feelings that they were very publicly shown to be wrong 5 years ago. Of course they're obsessed with refighting that war, and ivermectin is one of these. So a load of ivermectin cranks, having had the drug demonstrated useless against covid, are now obsessed with the idea it can treat anything else. Because if it does, it can feel like some sort of vindication that they were guzzling it by the truckload in 2020.
Confirmation bias is one hell of a drug
 

Agema

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Confirmation bias is one hell of a drug
Apparently NIH staff are calling Jay Bhattacharya "Podcast Jay", because he spends all his time doing talking to his computer screen rather than running the NIH. Allegedly, he's a figurehead and its his second-in-command doing the real work. That man is Matthew Memoli, a Trump crony who Trump made interim NIH director for the few months it took before Bhattacharya was confirmed.

Incidentally, the Dept. of Health has handed Memoli a $500 million research project to develop a new 'flu vaccine, and were kind enough to hand over vast sum without scientific evaluation of the proposal. Meanwhile the head of vaccines at the FDA (one Vinay Prasad) has also overruled the FDA's own scientific advice on spurious grounds to block a new mRNA 'flu vaccine from Moderna. Which I guess makes it a particularly great time to be handed a massive sum of money to research 'flu vaccines.

But fret not. If you or anyone you know is at risk of autism due to having a vaccine, you can always pop some leucovorin. Surely the science on that is sound, right?
 
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Gergar12

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Apparently NIH staff are calling Jay Bhattacharya "Podcast Jay", because he spends all his time doing talking to his computer screen rather than running the NIH. Allegedly, he's a figurehead and its his second-in-command doing the real work. That man is Matthew Memoli, a Trump crony who Trump made interim NIH director for the few months it took before Bhattacharya was confirmed.

Incidentally, the Dept. of Health has handed Memoli a $500 million research project to develop a new 'flu vaccine, and were kind enough to hand over vast sum without scientific evaluation of the proposal. Meanwhile the head of vaccines at the FDA (one Vinay Prasad) has also overruled the FDA's own scientific advice on spurious grounds to block a new mRNA 'flu vaccine from Moderna. Which I guess makes it a particularly great time to be handed a massive sum of money to research 'flu vaccines.

But fret not. If you or anyone you know is at risk of autism due to having a vaccine, you can always pop some leucovorin. Surely the science on that is sound, right?
This is what happens when you let a salesman run and be at the head of the executive branch. I love Mark Cuban, but I wouldn't want him as president for this reason even if I would pick him over 99% of the current Republican Party.
 

Phoenixmgs

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You are the one who brought up infectious dose.



...why would I? You haven't provided anything aside from your meaningless anecdotes. I'll stick with the well-established fact that fomite transmission is a common vector for various common viruses.
Infectious dose is a metric that is very much a best guess estimate and that's all it is. I only brought it up because you're acting like just being in contact with someone sick for a second means you can get infected.
We found low evidence, that transmission via hands and fomite followed by self-inoculation is the dominant transmission route in real-life indoor settings. We found moderate evidence, that airborne transmission either via large aerosols or small aerosols is the major transmission route of rhinovirus transmission in real-life indoor settings. This suggests that the major transmission route of RVs [Human rhinoviruses] in many indoor settings is through the air (airborne transmission).


You always fail to answer my basic common sense questions.
How would one ever go to a crowed indoor gathering for hours and not get sick? What you're trying to claim would make that literally impossible, yet we all know that happens all the time.
 

Silvanus

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We found low evidence, that transmission via hands and fomite followed by self-inoculation is the dominant transmission route [...]
"The dominant" route. Nobody is claiming that it's "the dominant" route.

Read beyond the summary, and your own link provides studies showing it can and does travel via fomite transmission, and not just in fringe cases.

You always fail to answer my basic common sense questions.
That ain't a common sense question at all. Your statement that "what I'm claiming" would make crowded indoor gatherings impossible without getting sick is just absolute horseshit. People have immune systems. Sometimes they succeed; sometimes they fail. The existence of transmission-- even transmission requiring relatively short exposure-- doesn't somehow make it a guarantee. That's just an obviously foolish extrapolation.
 

Phoenixmgs

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"The dominant" route. Nobody is claiming that it's "the dominant" route.

Read beyond the summary, and your own link provides studies showing it can and does travel via fomite transmission, and not just in fringe cases.



That ain't a common sense question at all. Your statement that "what I'm claiming" would make crowded indoor gatherings impossible without getting sick is just absolute horseshit. People have immune systems. Sometimes they succeed; sometimes they fail. The existence of transmission-- even transmission requiring relatively short exposure-- doesn't somehow make it a guarantee. That's just an obviously foolish extrapolation.
I read it... Common cold mainly transfers via air. You aren't going to get clusters of transmissions from people touching things in stores. I play board games with people at least 3 times a week and you all end up touching the same pieces/cards. How am I not getting sick?

You said the following:
We also know the infectious dose. The HID-50 and TCID-50. And so we know that someone can reach the infectious dose many times over by breathing in even a small fraction of someone else's sneeze.
What you said is not that it's theoretically possible to get sick from a fraction of a sneeze (which, ok, sure, probably extremely rare but possible), you said a small fraction of a sneeze holds many times over the infectious dose, thus it sounds rather likely to get sick then, doesn't it? Let's just say you have a 5% chance of getting sick from a small fraction of a sneeze (mainly so I can use a D20 for my example). When you are with people for hours in a crowded indoor area, you are not just getting one fraction of a sneeze worth of viral particles, you are getting that over and over and over and over and over again. If all those instances that keep occurring are all each 5% chances of getting sick, a 20 on a D20 is going to be rolled at some point and you should be getting sick, should you not? This is why these data points don't make sense and don't agree with basic observations of the world. Just like the Geno Smith example of the advanced metrics saying he's a top 5 quarterback made no sense because it's obvious from watching him play, he's at best a perfectly average quarterback. Sometimes the metrics don't mean what you think they mean.
 

Agema

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This is what happens when you let a salesman run and be at the head of the executive branch.
No, it's what happens when you let a corrupt, narcissistic fraudster run the executive branch.
 
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