Like a hypothetical bullet into my head, my original idea would be the first Grandia, updated voice-acting and a brush up on the 2.5D effect, a little tweak here and there and it would look great; but you said ANY series, and I'm biased to this choice on accordance to my longing for nostalgia...
So, to go absolutely whole hog on this premise, I want to see the game Project Nomads (not a series, sorry, but hear me out) not just rebooted, but refleshed, elaborated and with added features.
Here's a link, peeps probably never heard of this game anyway: http://en.wikipedia.org/wiki/Project_Nomads