I just ended a very sexual relationship that lasted about three months because she's moving away. Also, she turned psycho in the end. Apparently she already was psycho but I never saw it. Oh, the troubles of dating a former anorexic.
I would say my general nerdiness gets in the way of having a sex life more than the fact that I play games. I want a girl I can talk about nerdy stuff with. There are a few girls in my group that qualify, but they all have relationship issues. I'm also very particular. I want a girl that most would consider chubby but not morbidly obese and certainly not skinny as a twig.
Also, right now, I'm not taking any classes at my college, and that was by far the best way for me to meet women.
Still, I think most girls at my college are fully aware that most guys play video games. My roommate is a total Jock but he still loves the occasional Call of Duty 4.
So, gaming doesn't get in the way but being a picky, pretentious, and often elitist nerd does.