I'm gay, and before I knew I was gay it never really bothered me if I would be or not. Always thought whatever happens happens, no need to worry about it. And when I went, "yea I'm gay", it didn't change much at all for me. I just diverted my attention to the other gender.
Even before I came out to myself, I had always had an open mind about these kinds of things, one of my best friends is a tranny, and has wanted to be a woman since we met way back in grade 10. I had always been supportive of it for them, although nowadays it makes me sad because they were a really cute guy, and we always got along so well, jokingly tossing innuendo back and forth it public.
Strangely, I have rarely encountered homophobia amongst my friends, family and even strangers. Only one of my friends is a homophobe, and even then, we have stayed friends, and still meet up and go out for nights on the town with the gang, and it is always fun to torture him by acting stereotypical and watching him squirm. But he does get me back by getting everyone to agree to head off to a strip club, which is not a very good time for me.