Pick up lines are redundant, it doesn't matter what you say, it's about how you say it, you're body language ect..
A funny opener can help to initiate conversation but using actual pick up lines is AFC behaviour, IMO.
But if you're after some funnys;
Do you have any Italian in you?
Would you like some?
That shirt is very becoming on you, if I were on you, I'd be coming too.
If I could be any enzyme, I'd be DNA Helicase, so I can unzip you're genes.
You're feet must be tired, beccause you've been running through my head all night
Screaming.