Borg Wall'o'text inbound! Prepare to be soap-boxed! Resistance is... simple?
My grim realization came some months ago when I realized I was in a dead-end job and wasn't really able to do anything about it, having no prospects. I had plans and ideas for the future, but no way to achieve them. Also I had the same sort of soul-crushing revelation that anything I do is meaningless in the bigger picture. The Universe (and to a lesser extent Humanity) doesn't care about me or what I do, and will never notice my existence nor my passing.
However, after some mulling over I had an epiphany: The Universe (and to a lesser extent Humanity) can go fuck itself.
Two years ago, I was the best agent at my workplace because I had made a decision: They don't pay me enough for how hard I work every day, so I'll work for myself, and they can pay me for my time. It made no difference in my financial situation, but then every supervisor and manager over me started taking notice.
I've recently been promoted to Supervisor, after having been first bumped up to Trainer (they thought I was so awesome they wanted me to impart my badassery to new hires, three of which went on to be promoted quickly and one became the new trainer), then to Dispatcher (which made my Supervisor nervous because she was afraid I'd take her job), and my Manager is now wanting me to come along to meetings with clients.
I took that resolve and applied it to the rest of my life.
I'm currently relearning math from the ground up (it was always the subject that kicked my ass in school) since I'm aiming to become first an electrician, then an electrical engineer. During my retirement I'll be doing two things: being a foster parent and doing my best to give those kids a good home, and working on electrical experimentation to try to sort out a few ideas I have (make some science fiction reality).
When I am lying on my deathbed, I hope to be surrounded by a family I built out of abandoned souls, having given society technology only dreamt of. The sweetest part will be that I will have done this not for the good of anyone, but for my own personal satisfaction; because I felt they were jobs that needed doing, were worth doing, and I refused to do anything less than stellar.
I hope to die with that pride. Nevermind that the Universe (and to a lesser extent, humanity) won't care. I did, and that will be all that matters.