I will almost always make one female PC in any game, for two reasons. If I'm replaying a RPG I want to see the differences in NPC reactions. I also will get tired of the same male voice if I'm forced to listen to it over and over with the same dialogue and a change of voice is much appreciated. I never pretend to be female and when asked I'll always admit to being a guy. I like seeing how the developers approached sex and gender and sometimes the character I write up in my head (like say GW2), the sex doesn't matter and I already have 4 male characters.