Possibilities for Skye;JenSeven said:So, with mutant and alien out, what are we left with?
Time traveller? Something similar to X-23, but without the mutant connection? Genetic experiment?
Kree - A more human like Alien. would tie into Guardians of the Galaxy. But doesn't really leave a lot to work with. Especially since Fox has the Skrulls as part of the FF license. (also rule out Skrull)
Inhuman - Humans genetically engineered by the Kree. Now that could be fun.
Spider Woman - Genetically engineered by Hydra. Ties to SHIELD. Could be fun.
Scorpion II - Camilla Black, Genetically Engineered daughter of AIM Scientist Supreme and dweeb who later became MODOK. SHIELD operative. Sub D-Lister so readily available.
Mantis - The early pre cosmic version of Mantis. Half Vietnamese orphan girl with confusing cosmic destiny. Ties to Avengers, Guardians of the Galaxy, Silver Surfer.
secret Alien Love Child of Bruce Banner or the Hulk? - Sadly these exist. Both in male and female flavors.
Something totally horrible involving time travel? (pick any number of tiresome boring and contrived time lost refugees from some alternate future populating the Marvel books.)