all boss fights before recently have been trumped by Elizabeth Green from prototype. If you're not familiar with it, it's this giant biomass worm thing that's stationary in the middle of time square.
To start off, it's completely surrounded by infected, your standard "Larger, tough to beat" enemies AND the military. It will shoot projectiles at you if you're far away, which can manifest as either a large damage bile attack or machine gun fire of rocks. If you get too close to it it will hit you with its tentacle things. To as much as damage it you have to run up to it and kill two tentacle things and the big stock supporting its body, which have a good amount of health on their own, so it will fall down. Then you actually start damaging Green, which provided you don't get interrupted by any of the enemies you can get about a 6th of her health down before she gets back up and you have to repeat the whole process.
But the worst part is she has a 1 hit kill large radius attack which is used very liberally, and decimates two whole city blocks to every direction, which travels about as fast as you can run and offers the only warning as time slowing down for a split second, and while you're running from it she's shooting her machine gun rocks at you, which make you trip and get killed by the explosion thing. There's also NO checkpoints whatsoever while fighting this boss. So if you die, and you will, you have to start all over.
