Fallout Equestria. Littlepip aka The Bullet-magnet.A-D. said:EDIT: Forgot the most important Skill you have to have..Toaster Repair! If you know what i mean, you get a Cookie.
Double chocolate chip please.
The best builds for NV and 3 generally have
one combat skill
one get into stuff skill
one extra
Combat skills
Guns is a no brainer, even if you want to stealth or talk your way across the wasteland pick this for when the going gets tough. The other weapon skills such as energy or unarmed require a more special "special" allotment, if you want to wale on everything at close range buff up Str and End. If you pefer to go "pew pew" a high Luck will boost the obscene crit rate of energy weapons, (and make a killing in the casinos.)
Opening doors
Lockpick or Science take your pick, Science will be more situational but also open more quest options.
The odd one out
This one can be anything you choose, I would recommend Speech or Repair to either talk your way out or keep your equipment from falling apart.
Try the Vault wiki for more info
http://fallout.wikia.com/wiki/Fallout_Wiki