I guess I'll add my two cents to the pile.
My opinion of New Vegas gets worse the longer I play it. I have the PS3 version, and let me tell ya, it ain't all a basket of kittens. My top three teeth-gnashing bugs are:
Companions who get stuck somewhere and disappear
I never told Boone to wait for me, I just jumped into the river and swam over to a Deathclaw nest. After a heated round of genocide, I continued upriver and didn't pay attention to whether Boone was following me. By the time I realize Boone isn't shooting bad guys anymore, I've fast traveled away across the map. Boone hasn't come back. I've tried waiting. I've tried Novac. I've tried waiting IN Novac. Backtracking. And finally, saying "Fuck it". At least the Spotter perk still works.
Chug...chug...chug...FREEZE
This pretty much speaks for itself, but the frequency of it makes me want to give cigarettes to babies.
Vanishing NPCs
I've had NPCs decide, "Fuck this noise, I'm leaving for a job in Fallen Earth". Specifically, I cannot finish a quest for the Great Khans because Melissa jumped ship. There isn't even a body or a 'Dear John' letter. Nothing.
Honestly, I don't encourage anyone to buy it until they've read a heaping pile of reviews.
That being said. I fucking love this game. I know I shouldn't, but I totally do. The story blasts Fallout 3's out of the water, and has so many more connections with earlier Fallouts that I've actually put down the controller to call a friend and tell him to go to X location in the wasteland.
So there. Fuck you Obsidian, for making me love a broken game.