Oh, god yeah. I'm gonna be vague so it can't spoil, but enough so people who do know what I am talking about.
Walking Dead Season 1 got me (Poor Kenny, Poor Clem, Poor Lee and Season 2 felt really weak compared to the first).
Mass Effect 3 got me. Fanastic music, and having about 70 hours of bonding time with the characters helped to make me actually want them to live.
There was this bit in Homeland involving a phonecall in a prison that got me.
I cried when the racoon picked up a stick in Guardians of the Galaxy.
I cried when Sam carried Frodo.
I cried for Harry Potter when he lost both of the people who protected him. But not when the annoying thing died.
I cried about 40 times for FitzChivalry or the Fool.
I cried when Leonidus asked for his queen.
Yeah, I cry loads when it comes to films, books, games and such. Because I don't cry in real life, it can be nice to have a release.