wackymon said:
My response: I'd go with the Doctor, and just not give him a monologue, and kill him there. Thrice.
Pretty much. In a lot of cases, the reason he wins is because the villain lets him talk, meaning he either buys time for his friends to come to the rescue, or discovers your plan so when he craftily escapes he knows how to stop it, or you are just too distracted to realise that he has shimmied his way to the fire escape.
Not only that, but when he finally does come to stop you, he gives you the chance to surrender, flee and never return, a perfect opportunity to shoot him ... two times ... twice (double-tap for the kill, then a second double-tap to stop him regenerating).
OT: Definitely the Doctor for me. I'm not sure if I'd kill him (being a villain) or renounce my evil ways and travel with him forever.