Arkhangelsk said:
Family Guy. It's not as safe as Simpsons (although that show is good too, but it isn't as vulgar as South Park (which I hate).
South Park isn't just vulgarity. IT is actaully very cleverly written, even if you don't enjoy it. I used to watch it when I was younger because it was kids doing zany things and swearing. Watching it now it's a lot more complex than that.
OT: As you can tell, mine is South Park. I like family guy, but after 8 seasons that show is a little hit and miss. Some recent episodes are great, others not so much. South Park on the other hand has kept to the same standard, if not improved. There is the occasional slip up, but it's mostly really good.
Simpsons is a bit boring, though I did really like the movie. American Dad uses the Family Guy formula, but.... Worse. Futurama is brilliant, with excellent characterisation.