Considering Left 4 Dead 2 is one of my favourite games of all time, hells to the yes!
Got L4D2 for Christmas, managed to rack up 6,500 Infected kills in about 5 days. One morning, woke up at 9am, put it on, went on Scavenge and Campaign, looked at my watch and it was 4pm. 7 hours and I didn't notice it go by. THAT is immersion for you. So engrossed by the game, time just flies. Plus the fact that for weeks afterwards I kept on imagining Tanks, Hunters and Smokers in different hidey holes on my route to college, and my purchase of a Left 4 Dead 2 hoodie, I think I was a bit obsessed.
Left 4 Dead 3, if it can make me do this kind of thing again, is a day 1 purchase.