The Adult Swim infomercials, much like the rest of their programming, is hit or miss for me. Too Many Cooks was a hit, I dug the kind of clever way it managed to seemingly spoof ALL of television after awhile and my inner horror geek had a chuckle at the horror bits, in fact the chase scene with the woman whose name wouldn't go away with the theme song still playing around her too had me on the floor.
I can't read as much as you seem to into stuff like 12 Oz. Mouse though... (Though the praise you gave The Venture Bros. is well earned.) honestly most of the Matt Maiellaro created cartoons really just feel like stuff created to make stoned frat boys and 11 year olds who think Adult Swim is "edgy" will laugh at. Save for the Dr. Weird segments from early ATHF, I was never really a fan of his style. Then again maybe I'm a hypocrite because I know a lot of people can't stand Superjail! and while I wouldn't call it anything particularly special, I happen to LOVE Superjail aside from the somewhat transphobic elephant in the room. There was one pilot from Adult Swim a few years back though I really wish took off... Drinky Crow I think it was called? I need to watch that short again, it was fun.
