I thought season 1-3 were hilarious in a really stupid way. I thought everything after that felt too forced or too preachy. There are some occasional gems, but honestly, I can't bring myself to laugh at Family Guy anymore. Also, I'm starting to really get into newer American Dad. Originally I was kind of "eh" about it, but now, I think it's a pretty cool show... with some really disturbing stuff in it sometimes...
Also, I've been a little burnt on Futurama and Adventure Time. They're still pretty good, IMO, but they're far from perfect. I thought Young Justice was awesome, but at the same time, took itself a little too seriously and also had so many complicated convoluted stuff in it... guess that's why I don't read comic books.
Neglected to mention My Little Pony: Friendship is Magic or Gravity Falls, though...
Though I DO agree with Bob on one thing: Seth MacFarlane is an incredible talent, being a voice actor, INCREDIBLY singer, and actually a very good comedian. I freaking loved it when he hosted the Oscars! That doesn't make Family Guy any better, though from what I heard, his actual involvement in the writing of that show these days is limited, so I find it hard to blame him for why it sucks as opposed to liking some of the better stuff he's been involved in.
Oh, and Larry & Steve, FREAKING hilarious! And I AM kind of looking forward to that Family Guy/Simpsons cross-over coming next season, so there's that at least.