I enjoy when the devs make a point to have in game characters react accurately based on orientation. For example, I was in a cut scene in AC: O, picking up a quest from an NPC, and my character asked him where I could find the objective. The NPC said the word west, and then pointed in a direction. When I came out of the cutscene and had control again, the direction he pointed was actually west, and was in the general direction of the landmark he told me to look for.
Or when games like Horizon: Zero Dawn, have a stage in a quest, that is a crime scene analysis, and they set up the clues and orientation well enough that it actually made sense as you uncovered the stuff. Sure you could use the focus to home in on the points, but in one scene in particular, it was very easy to just deduce from looking around, what happened next. And then, when Aloy explained the sequence of events, it all lined up accurately with the locations discovered, and did make sense.
I like stuff like that.