I recently replayed this game too. As well as the unofficial patch, I added a "hard mode" mod that largely ruined the combat gameplay, as well as drastically altering the weapons (which by itself, I could have lived with). But poor choice of mods aside, it really is a very good game. A flawed masterpiece, alongside Alpha Protocol and other similarly ambitious, deep and engrossing games which simply failed in their execution.
I've played it through as Toreador once and Tremere once, properly, experimenting with different approaches and builds and had a great time with it. Since then however I discovered Malkavian clan and now cannot play anything else. I really want to try Nosferatu which, from what I hear, is a vastly different game. But Malk's are just too much fun and, as far as I can tell, the only clan none of whose abilities break the masquerade. The dialogue options, the Dementia ability, obfuscate all add up to a wonderful class to play.
The best thing about VTMB is that it makes you want more. It was good enough to suck us in, immerse us in a wonderful, grim world of undead and magic and had an interesting story, which according the wiki I spent a lot of time on reading up on the ins and outs of the WoD, is actually part of the canon leading up to gehenna. The biggest tragedy is that we'll never, ever see a follow up, there'll never be another offline, single player WoD RPG. It's very sad that we get CoDs and AssCreeds rehashed and regurgitated annually ad nausea, but the days of deep, single player, PC, story driven RPGs are over.