One. Legend of Zelda, Ocarina of Time. I deflected Ganondorf's energy balls with... a bottle.
Deux. Bioshock, final boss. I was blowing through my ammo and not getting anywhere, so I decided to try from the start of that fight one more time using only the wrench. It worked.
Set. Ok, really old here, and not technically a final boss. Chuck Yeager's Air-to-Air Combat. One of the most realistic flight simulators out there. One that has a self-installed envelope for you to push (as in for example, you pull up too hard from a dive when you're going too fast, your wings leave your plane for a better place.) One mission, effectively a bug out and return to base for a recon flight gone bad. Flying an RF-4, meaning no guns, meaning I have to run. Not only that, I have to run fast in a plane that has much, much, much slower acceleration on account of being the flying version of a bus with a huge engine. So, bogies fast and hot, 12 o'clock high, no guns. I try this mission dear god knows how many times. This time, I punch it and fly straight for them, weaving a little (literally, a little is all it can do.) I fly right past them, pull up into a fast climb, when they're coming after me again, I do half a loop, and turn over. Now I'm diving, facing the ground, throttle still wide open, and picking up speed. When I'm at about 1200 mph, and with ground looking like my biggest enemy (and not just literally) I cut the throttle and ease back on the stick. I swear its just on the edge of either falling apart or hitting the ground. When flat, I punch in the afterburners and check three things. First, altimeter. About 50 feet. Next, damage gauge (ok, not completely realistic, but still) about 70%. And finally, radar. Those planes chasing me are going about half as fast as me, as I now look at the air speed, which is Mach 2.
I checked with my brother afterwards, and all you had to do was roll over, cut throttle, do a half loop with throttle full on the bottom part, and not let up. Admittedly, I had a lot more fun though.
Shi. From way back in Wing Commander Academy. My brother and I took turns making harder and harder difficulty missions. My brother made one almost impossible with my plane flying in a minefield, and a pair of enemy Destroyers effectively. I decided to do it with a plane that doesn't really have good missiles (plural. It has one really good missile.) So, I decide to just fire the really good missile (pretty much a nuke) between the two ships and shoot it. It goes off, both ships are 99% dead, I'm 70% dead, mines are gone. I finish it with my slow as ball-shaped molasses energy guns.