Mafia 2, Chapter 14.
I was playing it on hard mode, and the fight on the docks isn't that bad, but once you get into the warehouse, there are like six or eight assholes shooting at you, on top of the "boss" throwing molotov cocktails at you from an elevated position.
So I always went in, picked somewhere to crouch down and try to take a few of the shooters out, but molotov douche would rain that crap down and it would damage me even if I was behind cover. I'd try to reposition, but his goons would either shoot me up, or they'd outright flank me before I got the chance.
So, it's about the eighth or ninth try and I'm just like.... "Fuck this, I'm at least killing the guys on the ground who flank me!" So I just run straight in, suicide mission style, and run under the platform where molotov man and his buddies are hanging out, and kill the two guys on the main floor. Wouldn't you know, the guys on the top floor, unable to see or reach me with gunfire anymore, start coming down the stairs. So I started shooting them as they came down.
With them all gone, killing this asshole with the molotovs was easy. So, a rage fueled strategy that I didn't expect to live through actually proved to be the smartest thing to do in that situation. Go figure.