It's sad to me how so many people seem to miss the parallels between the actions of the "Gay Supporters" and the actions of historical civil rights movement. Yes, homophobia is akin to racism, antisemitism, sexism, etc. The fact that people think they're different just shows how much more work gays need to do to be accepted. That includes "in your face" campaigns and gay pride parades (though the excessive representation of negative stereotypes in those parades is detrimental and unneccessary). The fact of the matter is that gays are discriminated against, and treated unequally. And no one ever got equality by toning it down and blending in. Would blacks have gotten their rights if they hadn't had marches or got in people's faces? Would women be able to vote if they had stayed at home and just wrote their congressmen? You need to get people's attention in these situations, and you need to call them out on it when they complain.
Being uncomfortable with homosexuality may be common and automatic but it is not okay. And calling homophobia a social disease is accurate. It is something negative and detrimental and it should be eradicated.
If the issue is really about PDAs then you wouldn't be bothered by the genders or the slogan. They would be completely irrelevant to you. If you feel you need to mention either, then the issue may have more to do with homosexuality than you conciously realize. In that case, you need to examine your feelings closely and unless you can come up with a truly rational reason for them, you need to find a way to dispel them.