Thank god I picked up Continuum Shift II at AX this year. I just love listening to Hazama troll everybody, let him go Unlimited, and then smash his face in.William Fleming said:Hazama from Blazblue, I just love his voice in the English voice. It's so over the top with his trolling and his LOLs, it's AWESOME. Personally, I prefer Hazama's voice over than the Joker in Arkham Asylum.
http://www.youtube.com/watch?v=srYxgMItVLM&feature=related
While I agree Red Dead Redemption and Mass Effect always had good voice-acting (Tali got infinitely better in Mass Effect 2), I'm surprised no one's mentioned Valkyria Chronicles yet. The cast just was a good fit all the way around.
Persona 3 and 4 was also good. I loved Vic as Junpei and Yuri Lowenthal as Yosuke.