Wayne's quick backstory is: Part of a team of 'Abomination Hunters' he was contracted by the NCR to clear the quarry at Sloan shortly after the second battle for Hoover Dam. Promised it was just a few Deathclaws they agreed. Obviously once there they were overmatched and his whole team, including his father but excluding the teams leader Dec (who left him for dead)
Arcade found him, took him to the followers and did they best they could, but they couldn't fix his knee. Arcade promised him his set of power armour to stop him using his legs, but a few days before the Enclave broadcast, he disappeared. Wayne is now in search of the Enclave to get the power armour he was promised and finally be pain free.
He doesn't hate the Legion like the followers, if anything he respects them for their honest approach to their intentions and their fierce loyalty. He does resent the NCR for their lies and manipulation though and blame them for his father's death. As far as the Enclave, he takes Gannons approach that they are 'not all bad', the Brotherhood are just another faction as far as he is concerned, he has no opinion on them... Yet...