They're all pretty equally messed up. Psychotrpic gas in the ventillation system, out of control cloning machines, forced genetic mutation experiments on the local population, audio induced insanity, forced eternal isloation, etc.
Some of the ones from other games are pretty screwy too, including the one that had 1 man and 1000 women, the one that had 1 occupant with no entertainment except a trunk full of sock puppets (he went insane in 18 months) and the one that was designed to not full seal, intentionally leaking radiation inside to cause mutations.
All the Vaults are pretty awful places.