My vote is torn between Brink and Duke Nukem Forever. Brink was a nice idea, and I think it would have worked out well if they'd have separated the single and multiplayer experiences. I got bored of the 'story' because it was just a sequence of multiplayer games, and I got bored of the multiplayer because it was just choosing levels of the stories, so I'd seen it all by the time I finished the Security campaign. I know how the Resistance one ended, because my brother always chooses rebels. So between us we did them both.
Duke Nukem Forever was just outright bad. Playable, but bad. Not exactly something you'd want people to catch you playing if they weren't 'in the know'. I don't like it for a couple of reasons. The first being that it sacrificed the Dukeness of the game by restricting you to two weapons (four if you're lucky) and replacing the kick with the gun-butt hit. Not that these are innately bad things - just don't pretend you're bringing back the Duke when you're just making a bad-humoured, tasteless Halo.
The guns were awful too. The only one that was satisfying to use was the shotgun. The ripper was the most ridiculous thing I've ever had the misfortune to use, and the 'Devastator' was vastly inferior to the rocket launcher, so I don't bloody know what was going on with that one.