I'm going to quote myself here:
"Not only does he watch Oprah, he's a personal friend of hers in the Duke Universe.
He has to be more than just what we see in-game for her to regard him in that manner.
The thing about Duke is that, yes, he is this rugged, crude man who indulges in women's sexuality, but unless I missed something, he's not bad about it. Sure, he's going to accept a horny young girl throwing herself on him, but when these same people are in danger, he rushes to their rescue, facing an empire of terrifying aliens single-handedly.
Is there any instance of Duke actually abusing a woman?
(Well, yes, in earlier versions of Duke Nukem, he may play Kevorkian to a few terribly mutated women, but when they're begging for a mercy-kill, I bet a lot of people would oblige)
What I see is that he's an intelligent, but coarse horndog with a fierce sense of chivalry."
If people can use him to promote feminism, (Real feminism, of course. Not this female-supremacist nonsense who claim to be femenists) then great!
Still, though, I don't see him as necessarily so mysogenistic. I mean, in his universe, he's extremely attractive. If an extremely desirable man went and saved my life and I was a horny, scantily-clad young woman, I'd prolly throw myself at him, too.
(I am a young woman, mind you. But asexual and quite modestly dressed.)