Creatures/Characters You'd Rather Never Fight Ever Again.

[Yanzo]

Those little crystal enemies with ridiculous long range insta drop magic attacks - Dungeon Siege

What, Shards? They're piss easy. Its the fucking Dark Stalkers that hang around the Shards in goddamn hordes that will kill you.

As for me? Bloodsuckers from Call of Pripyat. Especially the mission where you have to take out a nest of the bastards in pitch darkness.

They're not easy when I was going for a run as a solo magic user and I was getting half my hp taken off with a couple of zaaaaaaps. Most of my spells were either too slow moving/weak or just out of range.

Those dark stalkers were easy since I could just back away as they ran for me and keep magic blasting their balls off.

 

[TheTim]

The Imperial Star Destroyer from TFU, that was the worst thing i have ever experienced in my life, wanted to punch a hole through someone.

 

[Kashrlyyk]

Anything that hides or is invisible and loves to hinder you kiting in a tough battle.

 

[Osirisgod16]

All of the infinitely respawning enemies in the LEGO games. Every time I get to an area with those infinitely respawning faceless bastards who chip away at my health and studs I say a silent prayer that the fucker who designed them goes to Hell.

Good Job quoting Yahtzee.

OT: Freakin' Pukers. Anytime in Dead Space 2 that I saw a Puker I freaked out.

 

[GrimGrimoire]

The Imperial Star Destroyer from TFU, that was the worst thing i have ever experienced in my life, wanted to punch a hole through someone.

Oh, i forgot that one, the most anoying enemy in a Star Wars game EVER!

 

[Galaxy Roll]

Expert Mode Tanks in Left 4 Dead 2.

 

[fatal2704]

http://images.wikia.com/diablo/images/6/68/Duriel.gif

Duriel. Oh pain. took me like twenty town portal scrolls to defeat that bastard.

 

[RuralGamer]

The legendary bloatfly from New Vegas's Old World Blues DLC recently made my unwelcome acquaintance...
If you thought bloatflies were all just annoying, rather harmless vermin, you were very, very wrong.
Oh you think that armour will protect you? Not if it kills you in three hits!

 

[fatal2704]

Duriel. A thousand times Duriel.

He is so fucking overpowered it's not even funny.

*mutter* Prince of Pain indeed... *grumble*

Awww, you beat me to it. I had a level 22 Ice Sorc to deal with him, so i'd just set up a portal in front of the burial chamber, go in and pick off some health with glacial spike, die, and repeat. His boss chamber is just too small. Even teleport doesn't help.

 

[Ironbat92]

The Wretches from Gears of War. Those bastards are so annoying.

 

[Stalydan]

Ansem/Riku in Kingdom Hearts... because wow that cutscene gets annoying after the third time seeing it O_____o

 

[rutger5000]

Any humanoid mutant from S.T.A.L.K.E.R I hated every single one of them.

 

[S14]

Creepers(Minecraft)

^ this a 1000 times this

oh and this guy
http://youtu.be/JCDfkGisAtw

 

[renegade7]

My first is also from Oblivion: Bears. Fuckin' bears. They take a shit load to kill and they do a lot of damage to my weak, light armor wearing archer Scamps were a pain in the ass too.

Wizzrobes from the first zelda...they pissed me off a lot

Rogue drones (in EVE online). They are the nastiest of the normal NPC 'pirates', in my experience, and there is no monetary reward for killing them, and they don't drop loot.

Oh, also Geth Stalkers from ME1 if I'm playing a soldier (Adept's singularity fucks them up)

 

[Girl With One Eye]

Cazadors
They make me so sad.

Giant wasps suck.

Exactly my answer. Except that they don't make me sad, they make me RAGE!

 

[YonderTunic]

The freakin Flood on Halo still pisses me off, particularly that level on Halo 3 where you go save Cortana (I think that's her name....been a while) after the level with nothing BUT the Flood. I hate that level with all my might, and then some.

 

[Stephen Wo]

My retarded teammates on "Early Launch" from Brink. It's less physical fighting, but more fighting with them. Instead of protecting you while you hack the main objective, they have seizures about the command posts.

 

[alandavidson]

My dad. That guy is a balls crazy fighter.

Oh wait, we're talking about games... Um... probably the boss fights in Zulu Assault.

 

[Dalek Caan]

Cazadors from Fallout New Vegas. I need two partners at once just to take one down. Going for the wings is the best option.

 

[TheTim]

The Imperial Star Destroyer from TFU, that was the worst thing i have ever experienced in my life, wanted to punch a hole through someone.

Oh, i forgot that one, the most anoying enemy in a Star Wars game EVER!

Dude, that is the most annoying enemy that has ever been put in a game EVER