Oh god, so many things! Red Faction Armageddon, Assassin's Creed Brotherhood, The Witcher 2, Deus Ex Human Revolution, Gears 3, Monkey Island 2 Special Edition, MGS Rising, Bulletstorm, Portal 2, Hunted - The Demons Forge, Dead Space 2, Codename: Kingdoms, God of War - Ghost of Sparta, Kane & Lynch 2 - Dog Days (I actually enjoyed Kane & Lynch...), TRON Evolution, Castlevania - Lords of Shadow, Brink, Halo Reach
And I haven't even watched the Sony or Nintendo press conferenses yet...