I think it was the last episode of Heroes
' third season that I just threw my hands up and gave up on it. It had gotten too ridiculous and I just didn't care for the characters anymore. I remember when the fourth season came up, I only casually tuned in to the last couple minutes of the final season, where Clare exposed her power to the world, and I just thought to myself, "It was a good thing I didn't bother watching this season; they really jumped the shark here." Then it got cancelled, which confirmed my thoughts.
Then there's soap operas and reality shows like Hollyoaks
that I previously watched because of the addiction of certain storylines, before they too got too ridiculous and uninspired for my liking, to the point that I just began hating the series and the characters themselves as well (yes, Simon Cowell is playing the role of the "bad guy", which is why he gets booed whenever he makes an unnecessarily cruel statement about anyone who's standardly bad at singing cheesy crap pop songs).
Family Guy for me was an okay show that every now and then got somewhere near quality comedy, but there was a scene wherein Brian vomited for at least a minute after learning that he had slept with a transgender woman that was just played in this really uncomfortable way that I couldn't really forgive the show for. I mean, there didn't even seem to be a punchline (not that there'd be a good chance that any joke Seth could have made would have been much better)...it was just really disappointing.
Yeah, when my Science class watched that on the last day of school, I seemed to be the only one that wasn't laughing, and was just like, "Um...this is both annoyingly transphobic and not really funny..."
And then Seth McFarlane went on to genuinely say that he thought it was the best portrayal of transgender people on TV. Family Guy
is really a hit-and-miss show nowadays. There are some episodes that can at least get more than one good laugh out of you (because of the overall outlandish nature of the show), but others when there's either no joke other than "[insert pop culture reference] LOL" or they take the joke too far (e.g. Herbert's dragged-out fight against that old Nazi playing on the feeble gag of "old guys are really slow").