Call of duty (Seriously, that game series needed to end after CoD 4...)
Halo (They already said one game was the FINAL one, and yet still another one came out.)
Elder scrolls (Games are awesome, but it needs to make place for something new.)
Pokemon (Or at least, the black/red, gold/silver, etc series. Unless there's some real change/innovation, they need to stop making those.)
Final Fantasy (Imo after 10 it just got worse and worse.)
Mass Effect (Right now they're just at 'We ruined one game of a trilogy'. Let's not make that 'We ruined an entire franchise'. Because with more games, they probably will.)
Both C&C series. As in Red Alert and Tiberian series. (They got all that you could out of those series. And starcraft 2 did it better anyway. I doubt those two can top SC2 really, even with new games.)
Mario, sonic and zelda need to stay. Not because the games are good or anything, but because I want newer generations to also experience them. Well, unless the games become truly, utterly, entirely shitty one after another.