Metroid prime. I played that game though with 100%, speed runs, 100% speed runs, and even a power beam only play through using only other weapons when they were required (final boss, doors, etc). The first screen shot I ever took was my speed run time for a Nintendo power contest. My time was 3 hours 42 minutes. The best in the world was 3 hours 14 minutes (I don't know how I remember that, I just do).
I also beat the pants off of The Legend of Zelda Oracle of Ages/Seasons. I did every side quest, input every link password, got every ring, and got 16 heart containers, which took a LONG time, since there were only enough pieces of heart to get 13 heart containers with two more gained from linking, and the sixteenth had to be made from gyasha seeds which required about a million monster kills to turn into pieces of heart.
Pokemon sapphire. I got every pokemon possible and then some by linking with Colosseum, fire red/leaf green, etc., I got every piece of secret base furniture, and every super sketch, along with a nigh unbeatable team of lv 100s.
Edit: ooh! and let's add a list of Xbox 360 games I have every achievement for: CoD2, CoD4 (well, not really, but that's just a glitch), Halo 3, Rainbow 6 Vegas (not really again, but I got glitched out of that one too), and Bioshock (almost, just missing the Jackpot achievement, but that one is luck based, and I'm too lazy to go back and play the slot machines for hours just for 10 points)