Personally, I've never liked make-up and never wore it growing up. Of course, my mom's ultimatum when it came to make-up was "You can have make-up, or you can have zit medication". I choose the medication.
I have a complete total of 4 make-up products; foundation (though it's really just tinted moisturizer), zit spot concealer, blush (I think it's blush, I don't actually use it on my cheeks), and light lipstick.
There's pretty much only one reason I ever put any of these on; when it's important to make a good first impression, a.k.a the job interview. When more than half of the job ads I see read "professional appearance" as a requirement, that pretty much means well-dressed and make-up. Not clown-face make-up, mind you(unless you're applying to be a stripper or a porn star). And sometimes, it really does make my face look better. I'm in my twenties and still suffer from acne on occasion, and have eczyme on the bridge of my nose, around my eyes, and spots on the top, bottom and sides of my mouth. It's been a lot better as of late, but some days it flares up and I have a lot of red places on my face. Foundation covers that and makes my skin look, you know, like normal skin as opposed to skin that looks like I've been rubbing a brillo pad on sections of it. The blush or whatever goes around my eyes (little bit goes a long way). I rarely bother with the lipstick; I try to use it since my sister paid for this things and I don't want the money to go to waste.
But yeah, unless it's for a job or some other important occasion (like a wedding or something where I need to dress up), I don't bother with make-up. Mostly a hassle.