Bioshock's story and environment,
Silent Hill's atmosphere and story in part,
Gears of War combat.
A skinny, frail man wronged by all determined to save his daughter from the sadistic exploitation of a pseudo-anarchist for personal gains armed only with his trusty Tommy Gun and strange biological modifications to enhance his abilities in third-person-over-the-shoulder while facing hallucinations of his own personal demons as he is actually completely insane, believes himself to be searching for his daughter due to an accident involving head trauma upon arrival and was originally pillaging the city for the child prostitution trade and biological weapons stolen from objectivists who won't report the crimes, and upon self-realization, he has the choice to let Jack from the first game take the saved little sisters go to the surface or kill him and become a multimillionaire.
Game of the Year, anyone?