I've done a Maya run that was largely solo, no problems whatsoever. I even went the middle tree, the one that seems on the surface as more of a support, but it really makes you super tanky with the lifesteal and massive regen. and Phaselock is absurdly good and versatile, just lift up enemies from half the map away for easy sniper headshots (Vladof snpiers with 20+ round mags and high damage-per-shot are the best guns in the game, IMO. I feel that the guns may have been more balanced for consoles where headshots are trickier, because on PC autosnipers just rip through everything), or up close to put a badass enemy at the mercy of your shotgun. and it'll deal massive damage to enemies immune to the lifting.
Captcha: easy as cake