Definitely yes. I see the huge amount of damage it does first hand. For one thing, it breeds a horrible office culture in which "manning up" and the importance of machismo means working as many hours as possible so you can brag about it. Thus people - men especially - are encouraged to keep up with a stupid competition that results in them sacrificing their home life and proper R & R, and exhausting themselves to the point of them causing serious tiredness related mishaps. I work in a hospital, by the way.
I dislike the responsibilities and the level of authority I am expected to shoulder as a guy, though I am pleased to see this is already starting to change; it was my wife who asked me out (she is the second girlfriend of mine to do so), she works and she pays her share of everything. I dislike how my bearing as a man is based on work related achievement or wealth.
Worst of all, I hate the reputation I have by virtue of being a guy. I know that if a girl sees me in a dark alley, her instinct is to see me as a risk, regardless of anything I have actually done. This is because, statistically speaking, it would be ridiculous for her not to see me as a threat. Obviously, in these situations, one of us has it much worse off than the other (what with one living in fear of sexual assault, rape, harassment or violence - the other having to "just" live with being regarded as a possible perpetrator of any of those crimes), but I'd certainly wish this to stop being the case. I suppose it goes to show that most efforts to end the problems women have to face will automatically help men too.
I can't remember who it was, but they very correctly said that rape shouldn't be seen as a woman's problem - it is a man's problem, as a result of them being both the perpetrators, and the ones least likely to take an interest in the issue of stopping it.