I had the classic disc read error on my first PS2, but that seems common. More recently, my launch 20GB PS3 decided to die in quite a unique way. The large fan that blows air at the top of the unit just...stopped. I had no way of fixing it, and the system could not play select games for more than 15 minutes without shutting itself off. I was able to play everything but Demon's Souls, Sonic Unleashed, and I think Bioshock without it happening, but I had a feeling it was going to only get worse. It eventually got to the point where I could only play PSX/PS2 games without an almost instant overheat, so I traded the bricked system in and got a new 80GB which I upgraded to 160GB.
Unfortunately, the HDD I used to back up all of my saves decided to spontaneously not work, so I lost all of my progress, including at or near 100% files for Heavenly Sword, Sonic Unleashed, Bioshock, Mirror's Edge, Demon's Souls, Resistance 1 & 2, Dynasty Warriors 6, Ninja Gaiden Sigma, Metal Gear Solid 4, Resident Evil 5, Assassin's Creed, and countless other games. Still in the process of getting back to where I used to be in old games, since I refuse to use someone else's save. It sucks, but whatever. At least I get to play the games all over again, right?
EDIT: Oh! On the topic of PC errors, my laptop decided to adopt a "bad image error" whenever I open a program, but this happened after getting rid of a crapton of viruses that took days to destroy. Still have no idea where they came from, but I've left the bad image error since I don't want to have to reinstall Windows or whatever to fix it. The bad image error has been there so long, it now feels weird using another computer and being able to open programs without having to close out the bad image window. I tend to automatically click in the center of the screen to kill the popup even when it isn't there. My laptop also overheats at random, and decides to not be able to play videos every now and then. Fun fun fun.