You are killed by the last weapon you used in the last game you played.

[RelexCryo]

A .357 Super Magnum from Trent Easton's custom built, gold plated tiger skin-gripped .357 super magnum revolver in Perfect Dark.

 

[Barakiel]

I was murdered by three successive hits of five-of-a-kind poker hands.

Damnit Runespell.

 

[Kais86]

That would either be a fist, or a Heavy Viper transport, depending on how you define "weapon". I was playing a Behemoth in Champions Online, Behemoths punch, and throw large objects at people they don't like.

 

[Solo-Wing]

I got a keyblade to the back of my skull. OWWWWWWWWW!

 

[MajoraPersona]

I got punched to death by my own hands.

How could they betray me like that?

 

[Singularly Datarific]

ROFL!
I used the detonator for a self-deploying floatation device in Fallout New Vegas.
How would this work!?!

Some horrible mad man force fed you the flotation device before hand

Well, that's a better prospect than my imagination (inserted in other end) 0.0

 

[itsausernamewhatofit]

I'm OBJECTIONed to death. Ironically the lawyer who did it will now go on trial for murder.

 

[Kakashi on crack]

Well... I was just playing oblivion using my fists with a weakling character so...

I have a very painful bludgeoning death ahead of me O.O

 

[Trippy Turtle]

TnT in Minecraft. Awesome!

 

[Adamd1990]

Shotgun to the chest courtesy of a runner in Mirror's Edge. Hurts, dude, just hurts...

 

[Lord Merik]

the fork of horripilation. Ouch I think this will hurt.

 

[BanicRhys]

Flint and tinder from Minecraft.

 

[Hitokiri_Gensai]

uh oh. killed by a special ops team. DAMNIT! not again.

 

[Deadyawn]

So I just got killed by my own BARE DAMN HANDS.

 

[scorptatious]

The Pyro's Backscratcher?

Well, my back is kind of itchy... OH MY GOD AAARRGGH!

 

[Samuel Evans]

I guess I was killed by the Geth Pulse Rifle from ME2 with cryo rounds... So was I shot to death or frozen and then shattered?

 

[EvilMaggot]

M249 with Acog scope (3x4zoom) in Battlefield 3 alpha trial... ouch

 

[Gregg Lonsdale]

I was a scout last, so I guess I got a nature forced onto me.

 

[easternflame]

I get killed by the plasma launcher from Halo. So yeah, I get hit and have to wait for my death, GREAT

 

[FabiotheTurtle]

Stone sword to the head... Repeatedly...