Depends who he's killing, really. As has been noted the marketing stuff for this has been distinctly 'Anti-British' insomuch as they're bigging up the American heritage (see: last page with the flag) and having him murder almost solely Redcoats.Prince Regent said:Connor is half amerindian and half english. So no this game is not anti British.
Obviously the game itself might be different, but considering Ubisoft's past flubs not only with Assassin's Creed PR but as a company as a whole, we haven't been given much reason thus far to believe they will focus on Assassins vs. Templar instead of Evil Britain and the REAL AMERICAN FREEDOM LOVING ASSASSINS.