I don't know if moving away from Sci-Fi / Fantasy is necessary, seeing as Bioware is one of the few companies that produce (IMO), reliably enjoyable RPGs in those genres. What they need to do is continue DA2's trend of bucking the "Bioware Formula." Flaws aside, DA2 was a breath of fresh air after the constant stream of "Only you, the Jedi/Grey Warden/Spirit Monk, can collect the Star Maps/allies/Dragon Amulet pieces in order to stop the Sith/Blight/Emperor."
If it takes a genre change to accomplish this, then I guess I can live with that.
If it takes a genre change to accomplish this, then I guess I can live with that.