CronoT said:
Say what you want about Nintendo; the truth is, they PROTECT their IP's. We just pretend the Phillips CD-i never existed.
Metroid: Other M [http://tvtropes.org/pmwiki/lb_i.php?lb_id=13373815860B43920100&i_id=13373815860I43921400&p=1] would like to have a word with you.
This project, wherever it ends up, will be a lame duck. Keep in mind that this was a franchise that the creators had no plans for (and didn't script out any future plans for)
until EA came in and ordered further sequels. If anything, EA should be commended for giving Bioware the extra three month delay to finish the game. I shudder to think how much more of a buggy, rushed mess the game would be if they released in December 2011 instead of March 2012.
Any further installment, by necessity,
has to be either a prequel or a smaller-scale story. Trying to make an antagonist that "one-ups" the Reapers is going to fail, especially if it's set within the same time period as Shepard and his/her squadmates. The only foreseeable threat, the "tech singularity", by all in-game data, isn't set to show up for hundreds of thousands of years.
Bioware either has a choice of bridging the trilogy with prequels (which, if the response of the fanbase is any indication, will be a failure) or setting the action many, many centuries ahead and lose everything that made the games so unique (the world and characters they set up).
That said, if EA's marketing current strategy is any indication, it will either be filled with multiplayer or a F2P MMO. They turned their back on purely single-player games a long time ago.