I'd play a new Quest for Glory. It would need to retain the silly sense of humor, naturally-developing RPG stats, basis in real-world mythology, and charming, enchanted-feeling settings. I think it would do well to have a transfer to a more open-ended play style, though - maybe a bit more linear than an Elder Scrolls game, but the originals were really open-world games with very small worlds, limited by the technology that was available at the time.