Castlevania 5. Lords of Shadow was shit.
An actual sequel to Chrono Trigger. ENOUGH KINGDOM HEARTS BACKSTORY, SQUARE!
A DS port/remake of MOTHER3.
A guy can dream...
Final Fantasy X-3. Seriously, WTH Squeenix? Tidus came back at the end of X-2, so why not address that with a sequel?
Zelda II 3DS. The Adventure of Link is a perfectly good installment just
waiting for a remake. Do it to it, Nintendo!
Psychonauts 2. Everyone has already said it.
Nintendo vs. Capcom.
Y'know you want it. 
SEGA vs. Capcom. See above.
Mega Man in 3D. I can has? (Legends doesn't count.)
A 3D Sonic game that
doesn't suck. Do I win something?
Strong Bad's Even Cooler Game For Totally Awesome People. Or 'SBECG4TAP' for short.
Billiards Night At The Inventory. It'll have BLU Spy! And one of the Castle Crashers, or Meat Boy! And Guybrush! (And maybe even King Graham...)
And there's all the sequels I'm hoping for, and know will never be made.
