Civilization: I find it too slow of a game, as fighting takes forever, and seizing cities costs too much for the long run, so I always Science and Diplomacy my way through any conflict for some AI to randomly win, although they've been fighting 4 wars and lost plenty of them.
I tried to replay it today, and, after the 2.5 hours of 330 turns, I lost to Gandhi. Ragequit uninstall. It's one thing to be able to win by using tech and cultural dominance: it's another to just arbitrarily be decided (I know there's an option, but, c'mon, I wasted 2.5 hours)
Company of Heroes: It's like Dawn of War 2, only played as Imperial Guard without any fun units that add differentiation or a unit card to make sure you don't lose your unit that dies under three seconds of fire.
Empire:Total War: It's just lines of infantry shooting at each other whilst cavalry die and cannons just bomb shit. There's little tactical variation and battles aren't interesting
Serious Sam: You're just shooting the same groups of enemies with different guns. I know it's supposed to be a throwback, but a flimsy plot and having to rely on backwards motion doesn't keep me interested.
Pokemon & Final Fantasies: It's just turn-based combat that I don't like. Too slow and uninteresting
Castle Story: I know it's still in alpha, but I've become less interested with its building mechanics as I've toyed around with it. I hope it'll improve as I learn more about it as the game develops.