For all the people who apparently don't care about it, you sure are talking about it a lot.
As for me, I'm sort of a blank slate on this, I've never played the original, and I also never played the original Team Fortress, but I love TF2, doesn't necessarily mean I'm going to like DNF, but...Gearbox has done some pretty good games, I'll give them the benefit of the doubt as per usual.
I sort of glad actually, the graphics style seems to have changed a little since the original 3D Realms trailer, and, at the time it looked like they were using the same engine as Prey, which while the slick organic style suited, I didn't feel would suit DNF.