Graphics are ok (Skyrim level is ok)
BUT
animations, Animations and ANIMATIONS DAMMIT!!!
Better geometry and colision detection, no invisible walls or fake surfaces (even in places where noone ever could get- there were numerous times when I wore jetpack in FO3, tried to get to vantage point on roof and found out that there is no solid roof
)
And animations.
Also taking few notes from SkyUI would be great.
Also, did I mentioned animations?
P.S. Voiced character is interesting thing to experiment with (even if that would make modding even more restrictive)
P.P.S. And last but not least- animations.