Heh..I have a propensity to draw out games very greatly, due to my love of excessive grinding and getting lost.
Star Ocean 2 took me well into 80 hours, and I only got through half the game when my PS1 finally gave out. Not a surprise, considering I spent well over 300 hours on it playing Gran Turismo.
My history with Gran Turismo runs long and deep. I went through 4 copies of GT2 campaign discs, and 2 copies of arcade discs, no to mention 2 copies of GT3. Considering how long each CD ROM actually lasts, that's a surprising number of hours wasted on 1 series.
Most FF and other jRPGs takes me about 60 hours to beat on my first play through without side quests. With side quests, it usually approaches 120 hours, unless I use faqs..in which case it drops to about 100 hours. FF7 and 9 are my ultimate woe--I lost my safe early in the game's story in FF7 (right before escaping from Midgar) after weeks of mad grinding--I was level 30 before the real game even begins. So I got to do that twice..then I got lost on the way to Juno, leveled up until I can kill those crazy snow snakes (level 50-ish), etc etc. Overall, FF7 (the main one) eats up well over 150 hours of my life, not to mention the spin-offs.
FF9--I wreaked disc 2, bought another set, which turns out to not work with the last save (I think it was EU instead of US version like my first copy), so I got to start over again. Then my PS died, killing it (along with my SO2 file). I started up again on an emulator on PC and took another 20 or so hours before I gave up because I hate playing on keyboard.
My most memorable though has to be Suikoden. Reaching level 99 where the soft cap is 60 is by no means an easy feat.