Out of those options, I'd have to pick Harvest Moon, and it is definitely innovative, but innovation isn't really the same as changing gaming. Do you feel the influence of Harvest Moon in many games you play these days? Did Pikmin change gaming by simplifying RTS's and bringing them to a console crowd? Was Four Swords really the first four player co-op? And this is more of an actual question, since I've played the first but not the second: What did Fable 2 do that was so groundbreaking and a herald for change?
Hell, recently I'd argue that God of War changed gaming the most by bringing Quicktime events to the forefront and making them a prominent mechanic. Have you felt its influence in games? Now, sure it wasn't the first to do them, but you can't tell me there haven't been swarms more within the past 5 years because of God of War...
And beyond that, there have got to be games with more of an effect, and older ones at that.
I actually want to do a little more research into this because I have no idea how they qualify "change"... Does anyone have a link to the original article this is referencing?
And by the way, to whoever brings up "Influential", that is never mentioned (at least here). Changing gaming is not the same as being influential, presumably, but I'm having a hard time qualifying that due to a lack of original article. Their site is not easy to search through either.
EDIT: Found the article:
http://www.associatedcontent.com/ar...games_that_changed_gaming_without.html?cat=19
Now to read it.