My Guild Wars account got hacked into some time ago, I lost over 1000 hours, but I wasn't that pissed off. I had Obsidian armor and the rarest bow on my Ranger, and all of my other characters were wearing the 15k armor sets, I think my Assassin had like 3 or 4, but it wasn't important. I enjoyed earning them, and the differences were purely cosmetic, so it's not like I lost the best armor or weapon in the game, I merely lost the most expensive armor and weapon in the game. I remember having a sephis axe drop for me, requirement 8 with a +15%^50% mod on it, pretty much making me an in-game millionaire at the time. That was by far more enjoyable than the moment I bought my Obsidian armor (that was quite a "wooooo" moment though), and that's all that matters, not having the armor itself.
Plus, it gave me a reason to start again, which I did, and then I bought another account, on which I'm trying to get Obsidian armor for my Monk, but they nerfed quite a lot of the solo farms so I can only really do feather farming, which is very easy and very boring. I prefer farming the materials for the armor myself, which is a lot more fun, but no, it's nerfed.
Oh yeah, I lost my save on Oblivion too, which kinda sucked.. and Battlefield: Bad Connection 2 won't let me save, I've tried to start the campaign 3 times now and every time I quit and come back it says my save is corrupted. Fuck it, I'm not doing that first mission again. I don't know why I wanted to do it in the first place, the story will suck gigantic dick anyway.